Association of Diabetes and Hypertension With Brain Structural Integrity and Cognition in the Boston Puerto Rican Health Study Cohort

Yi Guan, Seyed Amir Ebrahimzadeh, Chia-Hsin Cheng, Weifan Chen, Tiffany Leung, Sherman Bigornia, Natalia Palacios, Mahdi O. Garelnabi, Tammy Scott, Rafeeque Bhadelia, Katherine L. Tucker, Bnag-Bon Koo
March 2022
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Abstract

The Boston Puerto Rican Health Study (BPRHS) is a longitudinal study following self-identified Puerto Rican older adults living in the Greater Boston area. Studies have shown higher prevalence of hypertension (HTN) and type 2 diabetes (T2D) within this ethnic group compared to age-matched non-Hispanic White adults. In this study, we investigated the associations of HTN and T2D comorbidity on brain structural integrity and cognitive capacity in community-dwelling Puerto Rican adults and compared these measures with older adult participants (non-Hispanic White and Hispanic) from the Alzheimer’s Disease Neuroimaging Initiative (ADNI) and National Alzheimer’s Coordinating Center (NACC) databases.

Type
Journal article
Publication
In Association of Diabetes and Hypertension With Brain Structural Integrity and Cognition in the Boston Puerto Rican Health Study Cohort Neurology Mar 2022, 10.1212
Weifan Chen
Weifan Chen
Ph.D in Computer Science

My research interests include cyber physical system and artificial intelligence.